Karen Friedman Agnifilo
Partner · Agnifilo Intrater LLP
Karen Friedman Agnifilo is a criminal defense attorney representing Luigi Mangione and a former Chief Assistant District Attorney in the Manhattan District Attorney’s office.
Defense Attorney
Positions
Partner · Agnifilo Intrater LLP
?–present
Lead defense counsel — Luigi Mangione
NY state and federal SDNY cases
?–present
Media
- Editor-provided
Cases
As party
- People v. Mangione (NY) — New York State prosecution of Luigi Mangione over the December 4, 2024 shooting of Brian Thompson. On September 16, 2025, Justice Gregory Carro dismissed the two terrorism counts — including the lone first-degree murder charge — as legally insufficient; second-degree murder is now the top of nine remaining counts. Trial set for September 8, 2026 before Justice Carro.
- US v. Mangione (SDNY) — Federal prosecution of Luigi Mangione in the Southern District of New York on charges of interstate stalking, electronic-communications stalking, murder through use of a firearm with a silencer, and a related firearms offense, arising from the December 4, 2024 shooting of UnitedHealthcare CEO Brian Thompson. Jury selection / trial set for October 13, 2026.